edgeR Result

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• We used the edgeR pipeline (McCarthy, Chen, & Smyth, 2012) to fit a negative binomial distribution for each gene in the mRNA.
• Pairwise comparisons between the three groups were then performed with a likelihood ratio test and adjusted for multiple testing using the Benjamini-Hochberg (Benjamini & Hochberg, 1995) method.
• Significant genes are labelled upregulated if the log fold change is positive and downregulated otherwise.